- Patients with diffuse scleroderma are at high risk for renal, lung and cardiac disease
- Severe skin involvement develops in the first three years of scleroderma disease
- Patients with severe organ involvement in scleroderma have a lower survival rate
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- To collaborate with the multicenter PRESS (Prospective Registry of Early Systemic Sclerosis)
- To identify predictors of scleroderma outcome
- To identify new treatments for diffuse scleroderma patients
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